Inhibition of telomerase using BIBR1532 enhances doxorubicin-induced apoptosis in pre-B acute lymphoblastic leukemia cells.

Bashash, Davood

Inhibition of telomerase using BIBR1532 enhances doxorubicin-induced apoptosis in pre-B acute lymphoblastic leukemia cells. [electronic resource] - Hematology (Amsterdam, Netherlands) Jul 2017 - 330-340 p. digital

Publication Type: Journal Article

1607-8454

10.1080/10245332.2016.1275426 doi


Aminobenzoates--pharmacology
Antibiotics, Antineoplastic--pharmacology
Apoptosis--drug effects
Caspase 3--metabolism
Cell Line, Tumor
Cell Proliferation--drug effects
DNA Replication--drug effects
Doxorubicin--pharmacology
Drug Synergism
Enzyme Activation--drug effects
G1 Phase Cell Cycle Checkpoints--drug effects
Humans
Naphthalenes--pharmacology
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma--genetics
Reactive Oxygen Species--metabolism
Telomerase--antagonists & inhibitors
Transcription, Genetic--drug effects