Design, synthesis and in vitro biological evaluation of oligopeptides targeting E. coli type I signal peptidase (LepB).
De Rosa, Maria
Design, synthesis and in vitro biological evaluation of oligopeptides targeting E. coli type I signal peptidase (LepB). [electronic resource] - Bioorganic & medicinal chemistry 02 2017 - 897-911 p. digital
Publication Type: Journal Article
1464-3391
10.1016/j.bmc.2016.12.003 doi
Cell Survival--drug effects
Dose-Response Relationship, Drug
Drug Design
Escherichia coli--enzymology
Hep G2 Cells
Humans
Membrane Proteins--antagonists & inhibitors
Models, Molecular
Molecular Structure
Oligopeptides--chemical synthesis
Serine Endopeptidases--metabolism
Structure-Activity Relationship
Design, synthesis and in vitro biological evaluation of oligopeptides targeting E. coli type I signal peptidase (LepB). [electronic resource] - Bioorganic & medicinal chemistry 02 2017 - 897-911 p. digital
Publication Type: Journal Article
1464-3391
10.1016/j.bmc.2016.12.003 doi
Cell Survival--drug effects
Dose-Response Relationship, Drug
Drug Design
Escherichia coli--enzymology
Hep G2 Cells
Humans
Membrane Proteins--antagonists & inhibitors
Models, Molecular
Molecular Structure
Oligopeptides--chemical synthesis
Serine Endopeptidases--metabolism
Structure-Activity Relationship