Therapeutic potential of the metabolic modulator phenformin in targeting the stem cell compartment in melanoma.

Petrachi, Tiziana

Therapeutic potential of the metabolic modulator phenformin in targeting the stem cell compartment in melanoma. [electronic resource] - Oncotarget Jan 2017 - 6914-6928 p. digital

Publication Type: Journal Article

1949-2553

10.18632/oncotarget.14321 doi


Aldehyde Dehydrogenase--metabolism
Antineoplastic Agents--pharmacology
Cell Line, Tumor
Cell Movement--drug effects
Cell Proliferation--drug effects
Cell Survival--drug effects
Dose-Response Relationship, Drug
Energy Metabolism--drug effects
Gene Expression Regulation, Neoplastic
Humans
Melanoma--drug therapy
Metformin--pharmacology
Microphthalmia-Associated Transcription Factor--genetics
Neoplasm Invasiveness
Neoplastic Stem Cells--drug effects
Phenformin--pharmacology
Phenotype
Skin Neoplasms--drug therapy
Spheroids, Cellular
Time Factors
Transfection