Enhancing the Cell Permeability and Metabolic Stability of Peptidyl Drugs by Reversible Bicyclization.

Qian, Ziqing

Enhancing the Cell Permeability and Metabolic Stability of Peptidyl Drugs by Reversible Bicyclization. [electronic resource] - Angewandte Chemie (International ed. in English) 02 2017 - 1525-1529 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1521-3773

10.1002/anie.201610888 doi


Amino Acid Sequence
Cell Membrane Permeability
Cell-Penetrating Peptides--chemistry
Drug Discovery
Drug Stability
HeLa Cells
Humans
I-kappa B Kinase--metabolism
Peptides, Cyclic--chemistry
Pharmacokinetics
Protein Interaction Maps--drug effects
Proteolysis
Solid-Phase Synthesis Techniques