Single-Nucleotide Polymorphism of CYP3A5 Impacts the Exposure to Tacrolimus in Pediatric Renal Transplant Recipients: A Pharmacogenetic Substudy of the TWIST Trial.

Billing, Heiko

Single-Nucleotide Polymorphism of CYP3A5 Impacts the Exposure to Tacrolimus in Pediatric Renal Transplant Recipients: A Pharmacogenetic Substudy of the TWIST Trial. [electronic resource] - Therapeutic drug monitoring 02 2017 - 21-28 p. digital

Publication Type: Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial

1536-3694

10.1097/FTD.0000000000000361 doi


Adolescent
Alleles
Area Under Curve
Child
Child, Preschool
Cytochrome P-450 CYP3A--genetics
Dose-Response Relationship, Drug
Female
Gene Frequency
Genotype
Humans
Immunosuppressive Agents--administration & dosage
Kidney Transplantation--methods
Male
Multidrug Resistance-Associated Protein 2
Mycophenolic Acid--administration & dosage
Pharmacogenetics
Polymorphism, Single Nucleotide
Tacrolimus--administration & dosage
Time Factors