Single-Nucleotide Polymorphism of CYP3A5 Impacts the Exposure to Tacrolimus in Pediatric Renal Transplant Recipients: A Pharmacogenetic Substudy of the TWIST Trial.
Billing, Heiko
Single-Nucleotide Polymorphism of CYP3A5 Impacts the Exposure to Tacrolimus in Pediatric Renal Transplant Recipients: A Pharmacogenetic Substudy of the TWIST Trial. [electronic resource] - Therapeutic drug monitoring 02 2017 - 21-28 p. digital
Publication Type: Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial
1536-3694
10.1097/FTD.0000000000000361 doi
Adolescent
Alleles
Area Under Curve
Child
Child, Preschool
Cytochrome P-450 CYP3A--genetics
Dose-Response Relationship, Drug
Female
Gene Frequency
Genotype
Humans
Immunosuppressive Agents--administration & dosage
Kidney Transplantation--methods
Male
Multidrug Resistance-Associated Protein 2
Mycophenolic Acid--administration & dosage
Pharmacogenetics
Polymorphism, Single Nucleotide
Tacrolimus--administration & dosage
Time Factors
Single-Nucleotide Polymorphism of CYP3A5 Impacts the Exposure to Tacrolimus in Pediatric Renal Transplant Recipients: A Pharmacogenetic Substudy of the TWIST Trial. [electronic resource] - Therapeutic drug monitoring 02 2017 - 21-28 p. digital
Publication Type: Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial
1536-3694
10.1097/FTD.0000000000000361 doi
Adolescent
Alleles
Area Under Curve
Child
Child, Preschool
Cytochrome P-450 CYP3A--genetics
Dose-Response Relationship, Drug
Female
Gene Frequency
Genotype
Humans
Immunosuppressive Agents--administration & dosage
Kidney Transplantation--methods
Male
Multidrug Resistance-Associated Protein 2
Mycophenolic Acid--administration & dosage
Pharmacogenetics
Polymorphism, Single Nucleotide
Tacrolimus--administration & dosage
Time Factors