Developmental Regulation of Mitochondrial Apoptosis by c-Myc Governs Age- and Tissue-Specific Sensitivity to Cancer Therapeutics.

Sarosiek, Kristopher A

Developmental Regulation of Mitochondrial Apoptosis by c-Myc Governs Age- and Tissue-Specific Sensitivity to Cancer Therapeutics. [electronic resource] - Cancer cell 01 2017 - 142-156 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

1878-3686

10.1016/j.ccell.2016.11.011 doi


Age Factors
Animals
Apoptosis
Doxorubicin--toxicity
Humans
Mice
Mitochondria--physiology
Neoplasms--drug therapy
Organ Specificity
Proto-Oncogene Proteins c-myc--physiology
bcl-2 Homologous Antagonist-Killer Protein--physiology
bcl-2-Associated X Protein--physiology