Mitochondrial morphology and cellular distribution are altered in SPG31 patients and are linked to DRP1 hyperphosphorylation.

Lavie, Julie

Mitochondrial morphology and cellular distribution are altered in SPG31 patients and are linked to DRP1 hyperphosphorylation. [electronic resource] - Human molecular genetics 02 2017 - 674-685 p. digital

Publication Type: Journal Article

1460-2083

10.1093/hmg/ddw425 doi


Animals
Cell Nucleus--genetics
Cells, Cultured
Dynamins
Female
GTP Phosphohydrolases--genetics
Humans
Male
Membrane Transport Proteins--genetics
Mice
Microtubule-Associated Proteins--genetics
Mitochondria--metabolism
Mitochondrial Proteins--genetics
Neurons--metabolism
Phosphoprotein Phosphatases--genetics
Phosphorylation--genetics
Spastic Paraplegia, Hereditary--metabolism