Skin Aging-Dependent Activation of the PI3K Signaling Pathway via Downregulation of PTEN Increases Intracellular ROS in Human Dermal Fibroblasts.

Noh, Eun-Mi

Skin Aging-Dependent Activation of the PI3K Signaling Pathway via Downregulation of PTEN Increases Intracellular ROS in Human Dermal Fibroblasts. [electronic resource] - Oxidative medicine and cellular longevity 2016 - 6354261 p. digital

Publication Type: Journal Article

1942-0994

10.1155/2016/6354261 doi


Cell Proliferation
Cells, Cultured
Cellular Senescence
Down-Regulation
Enzyme Activation
Fibroblasts--enzymology
Humans
Infant, Newborn
Male
NADPH Oxidases--metabolism
Oxidative Stress
PTEN Phosphohydrolase--genetics
Phosphatidylinositol 3-Kinase--metabolism
Phosphatidylinositol Phosphates--metabolism
Phosphorylation
Protein Kinase C-epsilon--metabolism
Reactive Oxygen Species--metabolism
Signal Transduction
Skin--enzymology
Skin Aging
Time Factors
Transfection