Scutellarin suppresses migration and invasion of human hepatocellular carcinoma by inhibiting the STAT3/Girdin/Akt activity.

Ke, Yang

Scutellarin suppresses migration and invasion of human hepatocellular carcinoma by inhibiting the STAT3/Girdin/Akt activity. [electronic resource] - Biochemical and biophysical research communications 01 2017 - 509-515 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1090-2104

10.1016/j.bbrc.2016.12.114 doi


Animals
Antineoplastic Agents, Phytogenic--pharmacology
Apigenin--pharmacology
Carcinoma, Hepatocellular--drug therapy
Cell Movement--drug effects
Cell Proliferation--drug effects
Glucuronates--pharmacology
Hep G2 Cells--drug effects
Humans
Liver Neoplasms--drug therapy
Male
Mice, Inbred BALB C
Microfilament Proteins--antagonists & inhibitors
Proto-Oncogene Proteins c-akt--antagonists & inhibitors
STAT3 Transcription Factor--antagonists & inhibitors
Vesicular Transport Proteins--antagonists & inhibitors
Xenograft Model Antitumor Assays