Myeloid-derived NF-κB negative regulation of PU.1 and c/EBP-β-driven pro-inflammatory cytokine production restrains LPS-induced shock.

Vanoni, Simone

Myeloid-derived NF-κB negative regulation of PU.1 and c/EBP-β-driven pro-inflammatory cytokine production restrains LPS-induced shock. [electronic resource] - Innate immunity 02 2017 - 175-187 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

1753-4267

10.1177/1753425916681444 doi


Animals
CCAAT-Enhancer-Binding Proteins--metabolism
Cells, Cultured
Female
Interleukin-1beta--genetics
Interleukin-6--genetics
Lipopolysaccharides--immunology
Macrophages--immunology
Macrophages, Peritoneal--immunology
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Promoter Regions, Genetic--genetics
Proto-Oncogene Proteins--metabolism
Sepsis--chemically induced
Trans-Activators--metabolism
Transcription Factor RelA--genetics
Transcriptional Activation