Rucaparib in relapsed, platinum-sensitive high-grade ovarian carcinoma (ARIEL2 Part 1): an international, multicentre, open-label, phase 2 trial.

Swisher, Elizabeth M

Rucaparib in relapsed, platinum-sensitive high-grade ovarian carcinoma (ARIEL2 Part 1): an international, multicentre, open-label, phase 2 trial. [electronic resource] - The Lancet. Oncology 01 2017 - 75-87 p. digital

Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study

1474-5488

10.1016/S1470-2045(16)30559-9 doi


Aged
Antineoplastic Agents--pharmacology
BRCA1 Protein--genetics
BRCA2 Protein--genetics
Carcinoma, Ovarian Epithelial
Drug Resistance, Neoplasm--drug effects
Fallopian Tube Neoplasms--drug therapy
Female
Follow-Up Studies
Germ-Line Mutation--genetics
Humans
Indoles--therapeutic use
International Agencies
Middle Aged
Neoplasm Recurrence, Local--drug therapy
Neoplasm Staging
Neoplasms, Glandular and Epithelial--drug therapy
Ovarian Neoplasms--drug therapy
Peritoneal Neoplasms--drug therapy
Platinum--pharmacology
Poly(ADP-ribose) Polymerase Inhibitors--therapeutic use
Poly(ADP-ribose) Polymerases--chemistry
Prognosis
Prospective Studies
Salvage Therapy
Survival Rate