Degradation of P-glycoprotein by pristimerin contributes to overcoming ABCB1-mediated chemotherapeutic drug resistance in vitro.

Yan, Yan-Yan

Degradation of P-glycoprotein by pristimerin contributes to overcoming ABCB1-mediated chemotherapeutic drug resistance in vitro. [electronic resource] - Oncology reports Jan 2017 - 31-40 p. digital

Publication Type: Journal Article

1791-2431

10.3892/or.2016.5230 doi


ATP Binding Cassette Transporter, Subfamily B--genetics
ATP Binding Cassette Transporter, Subfamily B, Member 1--metabolism
Cell Line, Tumor
Cells, Cultured
Doxorubicin--pharmacology
Drug Resistance, Multiple--drug effects
Drug Resistance, Neoplasm--drug effects
HEK293 Cells
Humans
Pentacyclic Triterpenes
Proteolysis--drug effects
Triterpenes--pharmacology