Pharmacodynamic study of the oral hedgehog pathway inhibitor, vismodegib, in patients with metastatic castration-resistant prostate cancer.

Maughan, Benjamin L

Pharmacodynamic study of the oral hedgehog pathway inhibitor, vismodegib, in patients with metastatic castration-resistant prostate cancer. [electronic resource] - Cancer chemotherapy and pharmacology Dec 2016 - 1297-1304 p. digital

Publication Type: Clinical Trial, Phase II; Journal Article

1432-0843

10.1007/s00280-016-3191-7 doi


Aged
Anilides--adverse effects
Hedgehog Proteins--antagonists & inhibitors
Humans
Male
Middle Aged
Prostate-Specific Antigen--blood
Prostatic Neoplasms, Castration-Resistant--blood
Pyridines--adverse effects
Zinc Finger Protein GLI1--genetics