Metformin treatment reduces temozolomide resistance of glioblastoma cells.

Yang, Seung Ho

Metformin treatment reduces temozolomide resistance of glioblastoma cells. [electronic resource] - Oncotarget Nov 2016 - 78787-78803 p. digital

Publication Type: Journal Article

1949-2553

10.18632/oncotarget.12859 doi


Animals
Antineoplastic Combined Chemotherapy Protocols--pharmacology
Brain Neoplasms--drug therapy
Cell Line, Tumor
Cell Movement--drug effects
Cell Proliferation--drug effects
Dacarbazine--analogs & derivatives
Dose-Response Relationship, Drug
Drug Resistance, Neoplasm
Gene Expression Regulation, Neoplastic
Gene Regulatory Networks
Glioblastoma--drug therapy
Humans
Inhibitory Concentration 50
Metformin--pharmacology
Mice, SCID
Neoplasm Invasiveness
SOXB1 Transcription Factors--genetics
Temozolomide
Time Factors
Transcriptome
Tumor Burden--drug effects
Xenograft Model Antitumor Assays