The wake-promoting drug modafinil stimulates specific hypothalamic circuits to promote adaptive stress responses in an animal model of PTSD.

Cohen, S

The wake-promoting drug modafinil stimulates specific hypothalamic circuits to promote adaptive stress responses in an animal model of PTSD. [electronic resource] - Translational psychiatry 10 2016 - e917 p. digital

Publication Type: Journal Article

2158-3188

10.1038/tp.2016.172 doi


Adaptation, Psychological--drug effects
Animals
Arousal--drug effects
Benzhydryl Compounds--pharmacology
Corticosterone--blood
Disease Models, Animal
Humans
Hypothalamo-Hypophyseal System--drug effects
Hypothalamus--drug effects
Male
Mental Recall--drug effects
Modafinil
Nerve Net--drug effects
Neuropeptide Y--physiology
Orexins--physiology
Pituitary-Adrenal System--drug effects
Rats
Rats, Sprague-Dawley
Stress Disorders, Post-Traumatic--prevention & control
Wakefulness--drug effects