Diosmin reduces cerebral Aβ levels, tau hyperphosphorylation, neuroinflammation, and cognitive impairment in the 3xTg-AD mice.

Sawmiller, Darrell

Diosmin reduces cerebral Aβ levels, tau hyperphosphorylation, neuroinflammation, and cognitive impairment in the 3xTg-AD mice. [electronic resource] - Journal of neuroimmunology 10 2016 - 98-106 p. digital

Publication Type: Journal Article

1872-8421

10.1016/j.jneuroim.2016.08.018 doi


Amyloid beta-Peptides--antagonists & inhibitors
Animals
Animals, Newborn
CHO Cells
Cerebral Cortex--drug effects
Cognitive Dysfunction--drug therapy
Cricetinae
Cricetulus
Diosmin--pharmacology
Dose-Response Relationship, Drug
Female
HeLa Cells
Humans
Inflammation--drug therapy
Male
Mice
Mice, 129 Strain
Mice, Transgenic
Phosphorylation--drug effects
tau Proteins--antagonists & inhibitors