Expression of CALR mutants causes mpl-dependent thrombocytosis in zebrafish.

Lim, K-H

Expression of CALR mutants causes mpl-dependent thrombocytosis in zebrafish. [electronic resource] - Blood cancer journal 10 2016 - e481 p. digital

Publication Type: Journal Article

2044-5385

10.1038/bcj.2016.83 doi


Animals
Calreticulin--genetics
Carcinogenesis--drug effects
Disease Models, Animal
Gene Expression Regulation, Neoplastic
Hematopoiesis
Hematopoietic Stem Cells--metabolism
Humans
Janus Kinase 2--genetics
Mutation
Myeloproliferative Disorders--drug therapy
Nitriles
Primary Myelofibrosis--drug therapy
Pyrazoles--pharmacology
Pyrimidines
Pyrrolidines--pharmacology
Receptors, Thrombopoietin--genetics
Signal Transduction--drug effects
Sulfonamides--pharmacology
Thrombocythemia, Essential--drug therapy
Thrombocytosis--drug therapy
Zebrafish