Mammalian target of rapamycin inhibition counterbalances the inflammatory status of immune cells in patients with chronic granulomatous disease.

Gabrion, Aurélie

Mammalian target of rapamycin inhibition counterbalances the inflammatory status of immune cells in patients with chronic granulomatous disease. [electronic resource] - The Journal of allergy and clinical immunology May 2017 - 1641-1649.e6 p. digital

Publication Type: Journal Article

1097-6825

10.1016/j.jaci.2016.08.033 doi


Adolescent
Adult
CD4-Positive T-Lymphocytes--drug effects
Child
Child, Preschool
Cytokines--immunology
Female
Granulomatous Disease, Chronic--immunology
Humans
Immunosuppressive Agents--pharmacology
Infant
Inflammation--immunology
Interleukin 1 Receptor Antagonist Protein--pharmacology
Male
Middle Aged
Monocytes--drug effects
Phagocytes--drug effects
Sirolimus--pharmacology
TOR Serine-Threonine Kinases--antagonists & inhibitors
Young Adult