Inhibition of ileal bile acid uptake protects against nonalcoholic fatty liver disease in high-fat diet-fed mice.

Rao, Anuradha

Inhibition of ileal bile acid uptake protects against nonalcoholic fatty liver disease in high-fat diet-fed mice. [electronic resource] - Science translational medicine 09 2016 - 357ra122 p. digital

Publication Type: Journal Article

1946-6242

10.1126/scitranslmed.aaf4823 doi


Animals
Bile Acids and Salts--metabolism
Ceramides--metabolism
Cholesterol--metabolism
Cyclic N-Oxides--administration & dosage
Diet, High-Fat--adverse effects
Feces
Gene Expression Regulation--drug effects
Glucose Tolerance Test
Ileum--drug effects
Liver--drug effects
Mice, Inbred C57BL
Non-alcoholic Fatty Liver Disease--pathology
Organic Anion Transporters, Sodium-Dependent--deficiency
Receptors, Cytoplasmic and Nuclear--agonists
Symporters--deficiency
Triglycerides--metabolism
Tropanes--administration & dosage