Thymus vulgaris alleviates UVB irradiation induced skin damage via inhibition of MAPK/AP-1 and activation of Nrf2-ARE antioxidant system.

Sun, Zhengwang

Thymus vulgaris alleviates UVB irradiation induced skin damage via inhibition of MAPK/AP-1 and activation of Nrf2-ARE antioxidant system. [electronic resource] - Journal of cellular and molecular medicine 02 2017 - 336-348 p. digital

Publication Type: Journal Article

1582-4934

10.1111/jcmm.12968 doi


Animals
Antioxidant Response Elements--genetics
Antioxidants--metabolism
Cell Nucleus--drug effects
Chromatography, High Pressure Liquid
Collagen Type I--genetics
Cytoprotection--drug effects
Elastin--metabolism
Fibroblasts--drug effects
Humans
Interleukin-6--biosynthesis
Male
Matrix Metalloproteinase 1--genetics
Mice, Hairless
Mitogen-Activated Protein Kinases--metabolism
NF-E2-Related Factor 2--metabolism
Phosphorylation--drug effects
Plant Extracts--pharmacology
Protein Transport--drug effects
RNA, Messenger--genetics
Skin--drug effects
Skin Aging--drug effects
Staining and Labeling
Thymus Plant--chemistry
Transcription Factor AP-1--metabolism
Transforming Growth Factor beta1--metabolism
Ultraviolet Rays