Drug Synergism of Proteasome Inhibitors and Mitotane by Complementary Activation of ER Stress in Adrenocortical Carcinoma Cells.

Kroiss, Matthias

Drug Synergism of Proteasome Inhibitors and Mitotane by Complementary Activation of ER Stress in Adrenocortical Carcinoma Cells. [electronic resource] - Hormones & cancer 12 2016 - 345-355 p. digital

Publication Type: Journal Article

1868-8500

10.1007/s12672-016-0273-2 doi


Adrenal Cortex Neoplasms--drug therapy
Adrenocortical Carcinoma--drug therapy
Antineoplastic Agents, Hormonal--pharmacology
Bortezomib--pharmacology
Cell Line, Tumor
Cell Survival--drug effects
Drug Synergism
Drug Therapy, Combination
Endoplasmic Reticulum Stress--drug effects
Endoribonucleases--genetics
Eukaryotic Initiation Factor-2--metabolism
Gene Expression Regulation, Neoplastic--drug effects
Humans
Leupeptins--pharmacology
Mitotane--pharmacology
Oligopeptides--pharmacology
Phosphorylation
Proteasome Inhibitors--pharmacology
Protein Serine-Threonine Kinases--genetics
X-Box Binding Protein 1--genetics