Huntingtons Disease Mice Infected with Toxoplasma gondii Demonstrate Early Kynurenine Pathway Activation, Altered CD8+ T-Cell Responses, and Premature Mortality.

Donley, David W

Huntingtons Disease Mice Infected with Toxoplasma gondii Demonstrate Early Kynurenine Pathway Activation, Altered CD8+ T-Cell Responses, and Premature Mortality. [electronic resource] - PloS one 2016 - e0162404 p. digital

Publication Type: Journal Article

1932-6203

10.1371/journal.pone.0162404 doi


Animals
Biomarkers
Brain--immunology
CD8-Positive T-Lymphocytes--immunology
Disease Models, Animal
Enzyme Activation
Female
Gene Expression
Huntington Disease--complications
Immunophenotyping
Indoleamine-Pyrrole 2,3,-Dioxygenase--genetics
Kynurenine--metabolism
Lymphocyte Activation
Mice
Mortality, Premature
Parasite Load
Phenotype
Toxoplasma
Toxoplasmosis--complications