Response to Programmed Cell Death-1 Blockade in a Murine Melanoma Syngeneic Model Requires Costimulation, CD4, and CD8 T Cells.

Homet Moreno, Blanca

Response to Programmed Cell Death-1 Blockade in a Murine Melanoma Syngeneic Model Requires Costimulation, CD4, and CD8 T Cells. [electronic resource] - Cancer immunology research 10 2016 - 845-857 p. digital

Publication Type: Journal Article

2326-6074

10.1158/2326-6066.CIR-16-0060 doi


Animals
Antibodies, Monoclonal--therapeutic use
Antibodies, Monoclonal, Humanized
Antineoplastic Agents--therapeutic use
CD4-Positive T-Lymphocytes--immunology
CD8-Positive T-Lymphocytes--immunology
Cell Line, Tumor
Dendritic Cells--immunology
Interferon-gamma--immunology
Lymphocytes, Tumor-Infiltrating--immunology
Macrophages--immunology
Melanoma--drug therapy
Mice, Inbred C57BL
Mutation
Programmed Cell Death 1 Receptor--antagonists & inhibitors
Proto-Oncogene Proteins B-raf--genetics
Xenograft Model Antitumor Assays