Reg4+ deep crypt secretory cells function as epithelial niche for Lgr5+ stem cells in colon.
Sasaki, Nobuo
Reg4+ deep crypt secretory cells function as epithelial niche for Lgr5+ stem cells in colon. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America 09 2016 - E5399-407 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1091-6490
10.1073/pnas.1607327113 doi
Animals
Colon--cytology
Colonic Neoplasms--metabolism
Epithelial Cells--metabolism
Intestine, Small--cytology
Mice
Neoplasm Proteins--genetics
Organoids--growth & development
Pancreatitis-Associated Proteins
Paneth Cells--cytology
Receptors, G-Protein-Coupled--genetics
Receptors, Notch--genetics
Stem Cell Niche--genetics
Stem Cells--cytology
Wnt Signaling Pathway--genetics
Reg4+ deep crypt secretory cells function as epithelial niche for Lgr5+ stem cells in colon. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America 09 2016 - E5399-407 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1091-6490
10.1073/pnas.1607327113 doi
Animals
Colon--cytology
Colonic Neoplasms--metabolism
Epithelial Cells--metabolism
Intestine, Small--cytology
Mice
Neoplasm Proteins--genetics
Organoids--growth & development
Pancreatitis-Associated Proteins
Paneth Cells--cytology
Receptors, G-Protein-Coupled--genetics
Receptors, Notch--genetics
Stem Cell Niche--genetics
Stem Cells--cytology
Wnt Signaling Pathway--genetics