The antiandrogen flutamide is a novel aryl hydrocarbon receptor ligand that disrupts bile acid homeostasis in mice through induction of Abcc4.
Gao, Xiaoxia
The antiandrogen flutamide is a novel aryl hydrocarbon receptor ligand that disrupts bile acid homeostasis in mice through induction of Abcc4. [electronic resource] - Biochemical pharmacology Nov 2016 - 93-104 p. digital
Publication Type: Journal Article
1873-2968
10.1016/j.bcp.2016.08.021 doi
Animals
Bile Acids and Salts--metabolism
Cell Line, Tumor
Flutamide--chemistry
Gene Expression Regulation--drug effects
Hepatocytes
Homeostasis--drug effects
Ligands
Mice
Mice, Inbred C57BL
Mice, Knockout
Models, Molecular
Multidrug Resistance-Associated Proteins--genetics
Protein Binding
Protein Conformation
Receptors, Aryl Hydrocarbon--metabolism
The antiandrogen flutamide is a novel aryl hydrocarbon receptor ligand that disrupts bile acid homeostasis in mice through induction of Abcc4. [electronic resource] - Biochemical pharmacology Nov 2016 - 93-104 p. digital
Publication Type: Journal Article
1873-2968
10.1016/j.bcp.2016.08.021 doi
Animals
Bile Acids and Salts--metabolism
Cell Line, Tumor
Flutamide--chemistry
Gene Expression Regulation--drug effects
Hepatocytes
Homeostasis--drug effects
Ligands
Mice
Mice, Inbred C57BL
Mice, Knockout
Models, Molecular
Multidrug Resistance-Associated Proteins--genetics
Protein Binding
Protein Conformation
Receptors, Aryl Hydrocarbon--metabolism