Evaluation of the pharmacokinetics of glibenclamide tablet given, off label, orally to children suffering from neonatal syndromic hyperglycemia.

Bouazza, Naïm

Evaluation of the pharmacokinetics of glibenclamide tablet given, off label, orally to children suffering from neonatal syndromic hyperglycemia. [electronic resource] - European journal of clinical pharmacology Nov 2016 - 1373-1379 p. digital

Publication Type: Clinical Trial, Phase II; Journal Article

1432-1041

10.1007/s00228-016-2119-9 doi


Administration, Oral
Blood Glucose--analysis
Child
Child, Preschool
Cytochrome P-450 CYP2C9--genetics
Dose-Response Relationship, Drug
Genotype
Glyburide--administration & dosage
Humans
Hyperglycemia--blood
Hypoglycemic Agents--administration & dosage
Injections, Subcutaneous
Insulin--administration & dosage
Models, Biological
Mutation
Off-Label Use
Potassium Channels, Inwardly Rectifying--genetics
Sulfonylurea Receptors--genetics
Syndrome
Tablets