Acquisition cancer stemness, mesenchymal transdifferentiation, and chemoresistance properties by chronic exposure of oral epithelial cells to arecoline.

Wang, Tung Yuan

Acquisition cancer stemness, mesenchymal transdifferentiation, and chemoresistance properties by chronic exposure of oral epithelial cells to arecoline. [electronic resource] - Oncotarget Dec 2016 - 84072-84081 p. digital

Publication Type: Journal Article

1949-2553

10.18632/oncotarget.11432 doi


3' Untranslated Regions
Aldehyde Dehydrogenase 1 Family
Animals
Antineoplastic Agents--pharmacology
Arecoline--toxicity
Carcinoma, Squamous Cell--chemically induced
Cell Line
Cell Transformation, Neoplastic--chemically induced
Cisplatin--pharmacology
Dose-Response Relationship, Drug
Drug Resistance, Neoplasm
Epithelial Cells--drug effects
Epithelial-Mesenchymal Transition--drug effects
Fluorouracil--pharmacology
Gene Expression Regulation, Neoplastic
Head and Neck Neoplasms--chemically induced
Humans
Hyaluronan Receptors--metabolism
Isoenzymes--metabolism
Mice, Inbred BALB C
Mice, Nude
MicroRNAs--genetics
Mouth Mucosa--drug effects
Mouth Neoplasms--chemically induced
Nanog Homeobox Protein--genetics
Neoplastic Stem Cells--drug effects
Octamer Transcription Factor-3--metabolism
Phenotype
Retinal Dehydrogenase--metabolism
SOXB1 Transcription Factors--genetics
Signal Transduction--drug effects
Squamous Cell Carcinoma of Head and Neck
Time Factors
Transfection