An effective tumor-targeting strategy utilizing hypoxia-sensitive siRNA delivery system for improved anti-tumor outcome.

Kang, Lin

An effective tumor-targeting strategy utilizing hypoxia-sensitive siRNA delivery system for improved anti-tumor outcome. [electronic resource] - Acta biomaterialia 10 2016 - 341-54 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1878-7568

10.1016/j.actbio.2016.08.029 doi


Animals
Cell Death
Cell Hypoxia
Cell Line, Tumor
Cell Proliferation
Down-Regulation
Endocytosis
Female
Gene Silencing
Gene Transfer Techniques
Luciferases--genetics
Mice, Inbred BALB C
Neoplasms--pathology
Particle Size
Polyethyleneimine--chemical synthesis
Proton Magnetic Resonance Spectroscopy
RNA, Small Interfering--administration & dosage
Treatment Outcome