Folate-conjugated gene-carrying microbubbles with focused ultrasound for concurrent blood-brain barrier opening and local gene delivery.

Fan, Ching-Hsiang

Folate-conjugated gene-carrying microbubbles with focused ultrasound for concurrent blood-brain barrier opening and local gene delivery. [electronic resource] - Biomaterials 11 2016 - 46-57 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1878-5905

10.1016/j.biomaterials.2016.08.017 doi


Animals
Blood-Brain Barrier--chemistry
Brain Neoplasms--genetics
Capsules--administration & dosage
DNA--administration & dosage
Electroporation--methods
Folic Acid--chemistry
Folic Acid Transporters--metabolism
Gene Transfer Techniques
High-Energy Shock Waves
Male
Microbubbles
Rats
Rats, Sprague-Dawley
Sonication--methods
Treatment Outcome