Discovery of a novel class of highly potent inhibitors of the p53-MDM2 interaction by structure-based design starting from a conformational argument.
Furet, Pascal
Discovery of a novel class of highly potent inhibitors of the p53-MDM2 interaction by structure-based design starting from a conformational argument. [electronic resource] - Bioorganic & medicinal chemistry letters 10 2016 - 4837-4841 p. digital
Publication Type: Journal Article
1464-3405
10.1016/j.bmcl.2016.08.010 doi
Crystallography, X-Ray
Drug Discovery
Fluorescence Resonance Energy Transfer
Molecular Conformation
Proto-Oncogene Proteins c-mdm2--antagonists & inhibitors
Tumor Suppressor Protein p53--antagonists & inhibitors
Discovery of a novel class of highly potent inhibitors of the p53-MDM2 interaction by structure-based design starting from a conformational argument. [electronic resource] - Bioorganic & medicinal chemistry letters 10 2016 - 4837-4841 p. digital
Publication Type: Journal Article
1464-3405
10.1016/j.bmcl.2016.08.010 doi
Crystallography, X-Ray
Drug Discovery
Fluorescence Resonance Energy Transfer
Molecular Conformation
Proto-Oncogene Proteins c-mdm2--antagonists & inhibitors
Tumor Suppressor Protein p53--antagonists & inhibitors