Fluorescent sensors of PARP-1 structural dynamics and allosteric regulation in response to DNA damage.

Steffen, Jamin D

Fluorescent sensors of PARP-1 structural dynamics and allosteric regulation in response to DNA damage. [electronic resource] - Nucleic acids research Nov 2016 - 9771-9783 p. digital

Publication Type: Journal Article

1362-4962

10.1093/nar/gkw710 doi


Allosteric Regulation
Animals
Biosensing Techniques
Catalysis
Cell Line
DNA Damage
Enzyme Activation
Enzyme Stability
Fluorescence Resonance Energy Transfer
Mice
Models, Molecular
NAD--chemistry
Poly (ADP-Ribose) Polymerase-1--chemistry
Protein Binding
Protein Conformation
Protein Interaction Domains and Motifs
Structure-Activity Relationship