Pre-existing anti-PEG antibodies are associated with severe immediate allergic reactions to pegnivacogin, a PEGylated aptamer.

Povsic, Thomas J

Pre-existing anti-PEG antibodies are associated with severe immediate allergic reactions to pegnivacogin, a PEGylated aptamer. [electronic resource] - The Journal of allergy and clinical immunology 12 2016 - 1712-1715 p. digital

Publication Type: Letter; Research Support, Non-U.S. Gov't

1097-6825

10.1016/j.jaci.2016.04.058 doi


Antibodies--immunology
Aptamers, Nucleotide--immunology
Clinical Trials, Phase III as Topic
Humans
Hypersensitivity, Immediate--immunology
Multicenter Studies as Topic
Polyethylene Glycols--adverse effects
Randomized Controlled Trials as Topic