Repurposing phenformin for the targeting of glioma stem cells and the treatment of glioblastoma.

Jiang, Wei

Repurposing phenformin for the targeting of glioma stem cells and the treatment of glioblastoma. [electronic resource] - Oncotarget Aug 2016 - 56456-56470 p. digital

Publication Type: Journal Article

1949-2553

10.18632/oncotarget.10919 doi


Animals
Apoptosis--drug effects
Brain Neoplasms--drug therapy
Cell Proliferation
Dichloroacetic Acid--pharmacology
Drug Repositioning
Gene Silencing
Glioblastoma--drug therapy
Glioma--drug therapy
HMGA2 Protein--antagonists & inhibitors
Humans
Hypoglycemic Agents--chemistry
Lentivirus
Mice
Mice, Nude
MicroRNAs--metabolism
Neoplasm Recurrence, Local
Neoplasm Transplantation
Neoplastic Stem Cells--drug effects
Phenformin--pharmacology
RNA, Long Noncoding--antagonists & inhibitors