Targeted tissue perfusion versus macrocirculation-guided standard care in patients with septic shock (TARTARE-2S): study protocol and statistical analysis plan for a randomized controlled trial.

Pettilä, Ville

Targeted tissue perfusion versus macrocirculation-guided standard care in patients with septic shock (TARTARE-2S): study protocol and statistical analysis plan for a randomized controlled trial. [electronic resource] - Trials 08 2016 - 384 p. digital

Publication Type: Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

1745-6215

10.1186/s13063-016-1515-x doi


Arterial Pressure--drug effects
Biomarkers--blood
Cardiotonic Agents--therapeutic use
Cardiovascular Agents--adverse effects
Clinical Protocols
Combined Modality Therapy
Data Interpretation, Statistical
Europe
Feasibility Studies
Fluid Therapy--adverse effects
Hemodynamics--drug effects
Humans
Lactic Acid--blood
Microcirculation--drug effects
Models, Statistical
Prospective Studies
Regional Blood Flow
Renal Replacement Therapy--adverse effects
Research Design
Respiration, Artificial--adverse effects
Sample Size
Shock, Septic--diagnosis
Time Factors
Treatment Outcome
Vasoconstrictor Agents--therapeutic use