Role of W181 in modulating kinetic properties of Plasmodium falciparum hypoxanthine guanine xanthine phosphoribosyltransferase.

Roy, Sourav

Role of W181 in modulating kinetic properties of Plasmodium falciparum hypoxanthine guanine xanthine phosphoribosyltransferase. [electronic resource] - Proteins 11 2016 - 1658-1669 p. digital

Publication Type: Journal Article

1097-0134

10.1002/prot.25107 doi


Amino Acid Substitution
Catalytic Domain
Escherichia coli--genetics
Gene Expression
Hydrogen Bonding
Inosine Monophosphate--chemistry
Kinetics
Molecular Dynamics Simulation
Mutation
Pentosyltransferases--chemistry
Phenylalanine--chemistry
Plasmodium falciparum--chemistry
Protein Interaction Domains and Motifs
Protein Structure, Secondary
Protozoan Proteins--chemistry
Recombinant Proteins--chemistry
Serine--chemistry
Structure-Activity Relationship
Substrate Specificity
Thermodynamics
Threonine--chemistry
Tryptophan--chemistry
Tyrosine--chemistry