Caspase-cleaved Tau-D(421) is colocalized with the immunophilin FKBP52 in the autophagy-endolysosomal system of Alzheimer's disease neurons.

Meduri, Geri

Caspase-cleaved Tau-D(421) is colocalized with the immunophilin FKBP52 in the autophagy-endolysosomal system of Alzheimer's disease neurons. [electronic resource] - Neurobiology of aging 10 2016 - 124-37 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1558-1497

10.1016/j.neurobiolaging.2016.06.017 doi


Aged
Aged, 80 and over
Alzheimer Disease--genetics
Autophagy
Brain--metabolism
Caspases
Cells, Cultured
Female
Humans
Lysosomes--metabolism
Male
Middle Aged
Neurofibrillary Tangles--metabolism
Neurons--cytology
Tacrolimus Binding Proteins--metabolism
Tauopathies--genetics
tau Proteins--metabolism