Early dihydrofolate reductase gene amplification events in CHO cells usually occur on the same chromosome arm as the original locus.

Trask, B J

Early dihydrofolate reductase gene amplification events in CHO cells usually occur on the same chromosome arm as the original locus. [electronic resource] - Genes & development Dec 1989 - 1913-25 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

0890-9369

10.1101/gad.3.12a.1913 doi


Animals
Cell Line
Chromosomes--metabolism
Diploidy
Drug Resistance--genetics
Fluorescent Dyes
Gene Amplification
Methotrexate--pharmacology
Mitosis
Nucleic Acid Hybridization
Plasmids
Polyploidy
Sister Chromatid Exchange
Tetrahydrofolate Dehydrogenase--genetics