Chronic glucocorticoid exposure suppressed the differentiation and survival of embryonic neural stem/progenitor cells: Possible involvement of ERK and PI3K/Akt signaling in the neuronal differentiation.

Odaka, Haruki

Chronic glucocorticoid exposure suppressed the differentiation and survival of embryonic neural stem/progenitor cells: Possible involvement of ERK and PI3K/Akt signaling in the neuronal differentiation. [electronic resource] - Neuroscience research Dec 2016 - 28-36 p. digital

Publication Type: Journal Article

1872-8111

10.1016/j.neures.2016.07.002 doi


Animals
Cell Differentiation
Cell Proliferation--drug effects
Cell Survival--drug effects
Corticosterone--adverse effects
Embryonic Stem Cells--cytology
Extracellular Signal-Regulated MAP Kinases--metabolism
Glucocorticoids--adverse effects
Neural Stem Cells--cytology
Neurons--cytology
Phosphatidylinositol 3-Kinases--metabolism
Proto-Oncogene Proteins c-akt--metabolism
Rats, Wistar
Signal Transduction