Targeting the HER Family with Pan-HER Effectively Overcomes Resistance to Cetuximab.

Iida, Mari

Targeting the HER Family with Pan-HER Effectively Overcomes Resistance to Cetuximab. [electronic resource] - Molecular cancer therapeutics 09 2016 - 2175-86 p. digital

Publication Type: Journal Article

1538-8514

10.1158/1535-7163.MCT-16-0012 doi


Animals
Antibodies, Monoclonal--pharmacology
Antineoplastic Agents--pharmacology
Carcinoma, Non-Small-Cell Lung
Carcinoma, Squamous Cell
Cell Cycle Checkpoints--drug effects
Cell Line, Tumor
Cell Proliferation--drug effects
Cetuximab--pharmacology
Disease Models, Animal
Drug Resistance, Neoplasm
ErbB Receptors--antagonists & inhibitors
Female
Head and Neck Neoplasms
Humans
Male
Mice
Protein Kinase Inhibitors--pharmacology
Receptor, ErbB-2--antagonists & inhibitors
Receptor, ErbB-3--antagonists & inhibitors
Squamous Cell Carcinoma of Head and Neck
Tumor Burden
Xenograft Model Antitumor Assays