ABCB1 (MDR1) induction defines a common resistance mechanism in paclitaxel- and olaparib-resistant ovarian cancer cells.

Vaidyanathan, Aparajitha

ABCB1 (MDR1) induction defines a common resistance mechanism in paclitaxel- and olaparib-resistant ovarian cancer cells. [electronic resource] - British journal of cancer 08 2016 - 431-41 p. digital

Publication Type: Journal Article

1532-1827

10.1038/bjc.2016.203 doi


ATP Binding Cassette Transporter, Subfamily B--antagonists & inhibitors
Acridines--pharmacology
Antineoplastic Agents--therapeutic use
Blotting, Western
Cell Line, Tumor
Drug Resistance, Neoplasm--genetics
Female
Gene Knockdown Techniques
Humans
Immunohistochemistry
Ovarian Neoplasms--drug therapy
Paclitaxel--therapeutic use
Phthalazines--therapeutic use
Piperazines--therapeutic use
RNA, Messenger--metabolism
Reverse Transcriptase Polymerase Chain Reaction
Tetrahydroisoquinolines--pharmacology
Verapamil--pharmacology