Protocol for a randomised control trial of methylnaltrexone for the treatment of opioid-induced constipation and gastrointestinal stasis in intensive care patients (MOTION).

Patel, Parind B

Protocol for a randomised control trial of methylnaltrexone for the treatment of opioid-induced constipation and gastrointestinal stasis in intensive care patients (MOTION). [electronic resource] - BMJ open 07 2016 - e011750 p. digital

Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

2044-6055

10.1136/bmjopen-2016-011750 doi


Adult
Analgesics, Opioid--adverse effects
Blood-Brain Barrier
Constipation--drug therapy
Critical Care
Female
Gastrointestinal Motility--drug effects
Humans
Laxatives--pharmacology
Male
Naltrexone--analogs & derivatives
Narcotic Antagonists--pharmacology
Quaternary Ammonium Compounds--pharmacology