Reengineering chimeric antigen receptor T cells for targeted therapy of autoimmune disease.

Ellebrecht, Christoph T

Reengineering chimeric antigen receptor T cells for targeted therapy of autoimmune disease. [electronic resource] - Science (New York, N.Y.) Jul 2016 - 179-84 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1095-9203

10.1126/science.aaf6756 doi


Animals
Autoantibodies--blood
Autoimmunity
B-Lymphocytes--immunology
CD3 Complex--chemistry
Cell Engineering
Cytotoxicity, Immunologic
Desmoglein 3--immunology
Disease Models, Animal
Humans
Immunologic Memory
Immunosuppression Therapy--methods
Mice
Pemphigus--immunology
Protein Structure, Tertiary
Receptors, Antigen, T-Cell--genetics
Recombinant Fusion Proteins--genetics
T-Lymphocytes--immunology
Tumor Necrosis Factor Receptor Superfamily, Member 9--chemistry