Histone modifications and p53 binding poise the p21 promoter for activation in human embryonic stem cells.
Itahana, Yoko
Histone modifications and p53 binding poise the p21 promoter for activation in human embryonic stem cells. [electronic resource] - Scientific reports 06 2016 - 28112 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
2045-2322
10.1038/srep28112 doi
Base Sequence
Cell Differentiation
Cell Line
Cyclin-Dependent Kinase Inhibitor p21--genetics
Epigenesis, Genetic
Fluorescent Antibody Technique, Indirect
Histones--metabolism
Human Embryonic Stem Cells--cytology
Humans
Induced Pluripotent Stem Cells--cytology
Methylation
Promoter Regions, Genetic--genetics
Protein Binding
Protein Stability
RNA Interference
RNA, Small Interfering--metabolism
Transcriptional Activation
Tumor Suppressor Protein p53--antagonists & inhibitors
Histone modifications and p53 binding poise the p21 promoter for activation in human embryonic stem cells. [electronic resource] - Scientific reports 06 2016 - 28112 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
2045-2322
10.1038/srep28112 doi
Base Sequence
Cell Differentiation
Cell Line
Cyclin-Dependent Kinase Inhibitor p21--genetics
Epigenesis, Genetic
Fluorescent Antibody Technique, Indirect
Histones--metabolism
Human Embryonic Stem Cells--cytology
Humans
Induced Pluripotent Stem Cells--cytology
Methylation
Promoter Regions, Genetic--genetics
Protein Binding
Protein Stability
RNA Interference
RNA, Small Interfering--metabolism
Transcriptional Activation
Tumor Suppressor Protein p53--antagonists & inhibitors