A c-Myc/miR17-92/Pten Axis Controls PI3K-Mediated Positive and Negative Selection in B Cell Development and Reconstitutes CD19 Deficiency.

Benhamou, David

A c-Myc/miR17-92/Pten Axis Controls PI3K-Mediated Positive and Negative Selection in B Cell Development and Reconstitutes CD19 Deficiency. [electronic resource] - Cell reports 07 2016 - 419-431 p. digital

Publication Type: Journal Article

2211-1247

10.1016/j.celrep.2016.05.084 doi


Animals
Antigens, CD19--genetics
B-Lymphocytes--physiology
Cell Death
Cells, Cultured
DEAD-box RNA Helicases--genetics
Genetic Complementation Test
Heterozygote
Mice, Inbred C57BL
Mice, Transgenic
MicroRNAs--metabolism
PTEN Phosphohydrolase--metabolism
Phosphatidylinositol 3-Kinases--metabolism
Proto-Oncogene Proteins c-myc--metabolism
Ribonuclease III--genetics
Signal Transduction