The effects of metformin and simvastatin on the growth of LNCaP and RWPE-1 prostate epithelial cell lines.

Pennanen, Pasi

The effects of metformin and simvastatin on the growth of LNCaP and RWPE-1 prostate epithelial cell lines. [electronic resource] - European journal of pharmacology Oct 2016 - 160-167 p. digital

Publication Type: Journal Article

1879-0712

10.1016/j.ejphar.2016.06.036 doi


Adenosine Triphosphate--metabolism
Apoptosis--drug effects
Autophagy--drug effects
Cell Count
Cell Cycle--drug effects
Cell Line, Tumor
Cell Proliferation--drug effects
Dose-Response Relationship, Drug
Drug Interactions
Epithelial Cells--cytology
Gene Expression Regulation, Neoplastic--drug effects
Glycolysis--drug effects
Humans
Male
Metformin--pharmacology
Necrosis--chemically induced
Prostate--cytology
Simvastatin--pharmacology