Elevated paternal glucocorticoid exposure alters the small noncoding RNA profile in sperm and modifies anxiety and depressive phenotypes in the offspring.
Short, A K
Elevated paternal glucocorticoid exposure alters the small noncoding RNA profile in sperm and modifies anxiety and depressive phenotypes in the offspring. [electronic resource] - Translational psychiatry 06 2016 - e837 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
2158-3188
10.1038/tp.2016.109 doi
Animals
Anxiety--genetics
Brain-Derived Neurotrophic Factor--genetics
Corticosterone--pharmacology
Depression--genetics
Exons
Fear--drug effects
Female
Gene Expression--genetics
Hypothalamo-Hypophyseal System--physiopathology
Insulin-Like Growth Factor II--genetics
Male
Maze Learning--drug effects
Mice, Inbred C57BL
MicroRNAs--genetics
Paternal Exposure
Phenotype
Pituitary-Adrenal System--physiopathology
Pregnancy
RNA, Small Untranslated--genetics
Sex Factors
Spermatozoa--drug effects
Elevated paternal glucocorticoid exposure alters the small noncoding RNA profile in sperm and modifies anxiety and depressive phenotypes in the offspring. [electronic resource] - Translational psychiatry 06 2016 - e837 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
2158-3188
10.1038/tp.2016.109 doi
Animals
Anxiety--genetics
Brain-Derived Neurotrophic Factor--genetics
Corticosterone--pharmacology
Depression--genetics
Exons
Fear--drug effects
Female
Gene Expression--genetics
Hypothalamo-Hypophyseal System--physiopathology
Insulin-Like Growth Factor II--genetics
Male
Maze Learning--drug effects
Mice, Inbred C57BL
MicroRNAs--genetics
Paternal Exposure
Phenotype
Pituitary-Adrenal System--physiopathology
Pregnancy
RNA, Small Untranslated--genetics
Sex Factors
Spermatozoa--drug effects