RAC1 activation drives pathologic interactions between the epidermis and immune cells.

Winge, Mårten C G

RAC1 activation drives pathologic interactions between the epidermis and immune cells. [electronic resource] - The Journal of clinical investigation 07 2016 - 2661-77 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural

1558-8238

10.1172/JCI85738 doi


Animals
Cell Differentiation--drug effects
Cell Proliferation
Coculture Techniques
Cytokines--metabolism
Epidermis--metabolism
Humans
Immune System
Inflammation
Keratinocytes--cytology
Male
Mice
Mice, Inbred NOD
Mice, SCID
Mice, Transgenic
Neoplasm Transplantation
Phenotype
Psoriasis--immunology
Skin--pathology
rac1 GTP-Binding Protein--metabolism