4-Phenylureido/thioureido-substituted 2,2-dimethylchroman analogs of cromakalim bearing a bulky 'carbamate' moiety at the 6-position as potent inhibitors of glucose-sensitive insulin secretion.
Pirotte, Bernard
4-Phenylureido/thioureido-substituted 2,2-dimethylchroman analogs of cromakalim bearing a bulky 'carbamate' moiety at the 6-position as potent inhibitors of glucose-sensitive insulin secretion. [electronic resource] - European journal of medicinal chemistry Oct 2016 - 338-351 p. digital
Publication Type: Journal Article
1768-3254
10.1016/j.ejmech.2016.05.042 doi
Animals
Aorta--drug effects
Carbamates--chemistry
Cromakalim--analogs & derivatives
Fura-2--metabolism
Glucose--pharmacology
Insulin--metabolism
Insulin Secretion
Islets of Langerhans--drug effects
Rats
Rats, Wistar
Vasodilator Agents--chemistry
4-Phenylureido/thioureido-substituted 2,2-dimethylchroman analogs of cromakalim bearing a bulky 'carbamate' moiety at the 6-position as potent inhibitors of glucose-sensitive insulin secretion. [electronic resource] - European journal of medicinal chemistry Oct 2016 - 338-351 p. digital
Publication Type: Journal Article
1768-3254
10.1016/j.ejmech.2016.05.042 doi
Animals
Aorta--drug effects
Carbamates--chemistry
Cromakalim--analogs & derivatives
Fura-2--metabolism
Glucose--pharmacology
Insulin--metabolism
Insulin Secretion
Islets of Langerhans--drug effects
Rats
Rats, Wistar
Vasodilator Agents--chemistry