GAPDH/Siah1 cascade is involved in traumatic spinal cord injury and could be attenuated by sivelestat sodium.

Huo, Jia

GAPDH/Siah1 cascade is involved in traumatic spinal cord injury and could be attenuated by sivelestat sodium. [electronic resource] - Neuroscience 08 2016 - 171-80 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1873-7544

10.1016/j.neuroscience.2016.05.054 doi


Active Transport, Cell Nucleus--drug effects
Animals
Apoptosis--drug effects
Disease Models, Animal
Drug Evaluation, Preclinical
Glyceraldehyde-3-Phosphate Dehydrogenases--metabolism
Glycine--analogs & derivatives
Interleukin-1beta--metabolism
Male
NF-kappa B--metabolism
Neuroprotective Agents--pharmacology
Nitric Oxide Synthase Type II--metabolism
Nuclear Proteins--metabolism
Random Allocation
Rats, Sprague-Dawley
Recovery of Function--drug effects
Signal Transduction--drug effects
Spinal Cord--drug effects
Spinal Cord Injuries--drug therapy
Sulfonamides--pharmacology
Tumor Necrosis Factor-alpha--metabolism
Ubiquitin-Protein Ligases--metabolism
Seven in Absentia Proteins