V-akt murine thymoma viral oncogene homolog 3 (AKT3) contributes to poor disease outcome in humans and mice with pneumococcal meningitis.

Valls Serón, Mercedes

V-akt murine thymoma viral oncogene homolog 3 (AKT3) contributes to poor disease outcome in humans and mice with pneumococcal meningitis. [electronic resource] - Acta neuropathologica communications 05 2016 - 50 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2051-5960

10.1186/s40478-016-0320-9 doi


Animals
Carrier Proteins--genetics
Cytokines--cerebrospinal fluid
Disease Models, Animal
Dynactin Complex--genetics
Genetic Association Studies
Genetic Predisposition to Disease
Histocompatibility Antigens Class I--genetics
Humans
Male
Membrane Proteins--genetics
Meningitis, Pneumococcal--genetics
Mice, Inbred C57BL
Mice, Knockout
Middle Aged
Netherlands
Prospective Studies
Proto-Oncogene Proteins c-akt--deficiency
Survival Analysis
Treatment Outcome